Neurosimulator · Latest from the lab

A scan segmented twice in the browser, on lifetime curves

2026-10-07T05:01:00Z

A public, defaced T1 segmented twice on WebGPU inside a browser tab, brainchop then FastSurferVINN, and its grey matter, white matter and ventricles placed on BrainChart's lifetime curves.

Methods Recorded in headless Chrome from the Scan Lab: a defaced T1 from the IXI dataset, conformed in the tab; brainchop MeshNet (TF.js on WebGPU), then FastSurferVINN 2.5.4 as ONNX (onnxruntime-web 1.30 on WebGPU); grey matter, white matter and ventricle volumes placed on BrainChart's centile curves (Bethlehem et al. 2022); then the labelled brain in the app's WebGPU engine. The scan never left the tab: 332 requests, none off-origin · predicted

Brain · in development

Stroke paints its tissue model onto each brain region

2026-10-07T01:19:42Z

Stroke's tissue model now shows on the brain itself: each structure is tinted by its share of penumbra, core and reperfused tissue as the scene's clock runs. Shown: a left M1 clot, 24 h untreated.

Methods The Stroke scene's tissue-fate model: openBF v5 blood flow on one public IXI head's geometry and the Liu et al. 2023 arterial territories, coupled to a fixed relative-CBF/time injury rule. Each structure is tinted by its share of 2 mm voxels in penumbra, core and reperfused tissue at the scene's time, from tables for 44 runs whose totals match each run's own to 0.01 mL. Drawn by the app's WebGPU engine · simulated, derived

Brain · live in the app

The Visible Human skeleton gains its hands and feet

2026-10-06T21:25:47Z

Body's anatomy pack 0.4.1 adds the forearms, hands, lower legs and feet, segmented from the Visible Human CT. Both elbows are still missing: they lie outside the CT's scanned field.

Methods Visible Human Male (NLM), one donor; face removed. The skeleton is TotalSegmentator 2.18.0's segmentation of its CT (Wasserthal et al. 2023), the total and appendicular-bones models, with no reader correction; each vertex is coloured from the measured cryosection colour volume. Neutral study renders of the skeleton, front and left, cut 40 mm below the skull (Blender 5.2 Cycles) · derived

Body · in development · Body opens 9 Oct

Body's dive from the heart to a filament runs end to end

2026-10-06T19:54:19Z

Body's Explore now steps through a 42-second dive in seven stages, from the whole body down to a heart-muscle filament, loading each stage's data in turn. Shown: the heart, then the myofibril.

Methods Left, the heart: the Human Reference Atlas 3D reference heart, male, v1.3 (Browne and Schlehlein 2024), a reference model made from the Visible Human Male, with its coronary vessels from the HRA blood vasculature. Right, the myofibril: adult mouse heart muscle, chemically fixed and imaged by electron tomography, with the depositors' own traces of its T-tubules, junctional SR and mitochondria (Cell Image Library CCDB:3611; Hoshijima et al. 2004; Hayashi et al. 2009). Body's Explore at 9 s and 16 s of 42, drawn by the app's WebGPU engine · derived

Body · in development · Body opens 9 Oct

Genome mode: the human genome on one map

2026-10-06T19:37:32Z

From whole chromosomes down to single letters, with genes, ClinVar, conservation and AlphaGenome's prediction for every possible single-letter change. A gene's card links into Brain and Body.

Methods Hilbert map of GRCh38 (the 1000 Genomes Project's analysis set), coloured by AlphaGenome Atlas variant impact (AVI) scores (Cheng et al. 2026; model: Avsec et al. 2026): each letter shows the highest score of its three possible single-letter changes, on the Phred scale. Other layers and the gene card: GENCODE v46 (Frankish et al. 2023); ClinVar, release of 28 Sep 2026 (Landrum et al. 2018); UCSC phyloP 100-way (Pollard et al. 2010); AlphaMissense (Cheng et al. 2023) · predicted

Genome · in development · Reaches the app after 9 Oct

One simulated minimal cell grows and divides, replayed

2026-10-06T19:35:15Z

We now replay a whole cell cycle of the minimal cell JCVI-syn3A ourselves, from the published 4D whole-cell model, with its particle counts exact on all 7,201 frames. Shown: dividing, at 95 minutes.

Methods One frame (t = 5,700 s) of trajectory MinCell_1 from the 4D whole-cell model of Thornburg et al., Cell 2026 (Zenodo 15579159): Lattice Microbes reaction–diffusion on a 10 nm lattice. All 137,400 particles are drawn at their lattice sites, with 26,945 chromosome and 17,062 membrane sites; the near half is cut away. Drawn counts equal the frame's. Small molecules are simulated well mixed and not drawn. · simulated

Cells · in development

The Visible Human male, with the HRA organs placed inside

2026-10-06T19:32:52Z

Body's anatomy pack 0.4.0: the Visible Human male's anatomy, with the Human Reference Atlas organ parts and heart placed inside it by a rigid fit to the spine and pelvis.

Methods Visible Human Male (NLM), one donor; face removed; its CT segmented with TotalSegmentator (Wasserthal et al. 2023). HRA v2.5 organ parts and heart (HuBMAP), placed by a rigid torso/pelvis fit; held-out bone-centroid RMS 3.9 mm. Neutral study render, cut 40 mm below the skull, skin hidden (Blender 5.2 Cycles) · derived, reference

Body · in development · Body opens 9 Oct

The Dose–PET workbench is live in Labs

2026-10-06T17:55:59Z

The Dose–PET workbench opened in the app's Labs: measured PET from four published studies beside a frozen model's predictions and three trivial baselines, each record traced to its source.

Methods Frozen conditional equilibrium at measured parent plasma concentration, using inherited fu, Kp,uu and Ki assumptions, against measured PET binding-potential changes (Fitzgerald 2000, Gründer 2006, Madsen 2019, Lundberg 2012). Assay records from ChEMBL 37, the NIMH PDSP Ki database and the IUPHAR/BPS Guide to Pharmacology 2026.3, with Rickli 2016; normative density from the Hansen 2022 receptor atlas on Schaefer-400 parcels (Schaefer 2018). Numerical reproduction is not biological validation. Shown: clozapine at D2 (Gründer 2006, 15 people), where the model's lowest point error is not a robust win · derived

Labs · live in the app

A recorded walk replayed with 80 muscle paths

2026-10-06T16:33:42Z

A recorded walking trial replayed on a musculoskeletal model: 80 leg muscle paths, their activation estimated frame by frame. Shown: a 1.2-second excerpt, drawn as a figure, not by the engine.

Methods The Rajagopal et al. 2016 full-body model and its original overground walking trial, in OpenSim 4.6 (Seth et al. 2018): measured markers drive inverse kinematics, measured ground forces drive static optimisation, so the activation is estimated, not measured. Modelled bone geometry and 80 lower-limb paths; arms and trunk neutral. Exploratory and unscored; path thickness is illustrative. Shown: a Matplotlib figure of a 1.2-second excerpt in two views, every stored 100 Hz sample once at half speed, with eight paths' estimated activation as a heatmap · derived

Body · in development · Body opens 9 Oct